A Top-20 matchup awaits us on Saturday in Bloomington as the No. 9 Indiana Hoosiers take on the No. 18 USC Trojans. It's a pivotal showdown for both teams, as both the Hoosiers and Trojans are firmly in the Big Ten race as well as the College Football Playoff hunt entering Week 11.
Both teams are coming off a bye in Week 10. Indiana has won its last two games in overtime, with their most recent victory coming in thrilling fashion against Minnesota by a score of 23-16. On the other side, USC took down Ohio State 30-18 in its last showing. Although, the Buckeyes were without starting quarterback Julian Sayin in that contest.
Kick-off is slated for 3:30 p.m. ET. With the anticipation continuing to build, here is a closer look at the final Indiana vs USC betting odds, as well as a score prediction.
Final Indiana vs USC betting odds in Week 11
Playing at home, professional oddsmakers are giving the edge to the Hoosiers in this matchup. Specifically, Indiana is favored by 9.5 points over USC on DraftKings Sportsbook. Here is a full look at the Indiana vs USC betting odds for this Week 11 clash:
Moneyline
USC (+270)
Indiana (-340)
Spread
USC +9.5 (-108)
Indiana -9.5 (-112)
Total
Over 51.5 (-112)
Under 51.5 (-108)
Both the Hoosiers and Trojans have struggled to cover the spread this season. Indiana is 8-1 overall, but has covered the spread in just one of its nine games. USC owns a record of 7-2, but is just 3-6 against the number.
Furthermore, both teams have played in plenty of low-scoring games. The Under is 6-3 for Indiana and 5-4 for USC so far this season.
Game odds refresh periodically and are subject to change.
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Indiana vs USC preview and score prediction
With both teams having an extra week to rest up and prepare, coaching matters even more. In that scenario, Curt Cignetti gives Indiana the edge of Lincoln Riley and USC. The Trojans have made some strides this season, but have continuously come up short in games of this magnitude during Riley's tenure.
USC is also at a disadvantage playing on the road. The Trojans have struggled mightily when traveling across multiple time zones since joining the Big Ten. The last time they did so, USC got boat-raced by Wisconsin to the tune of a 24-7 loss in Madison on October 24.
Indiana has home field advantage and a big edge on the defensive end. The Hoosiers rank 2nd in the Big Ten in total defense, and are allowing just 259.2 yards of offense per game to their opponents. USC’s defense has looked better at times, but consistency continues to be an issue. Plus, USC's biggest win of the season two weeks ago against Ohio State came against Luke Fahey as opposed to Julian Sayin. In total, the Trojans rank 14th in the Big Ten by surrendering 24.2 points per game. Indiana wins and covers 34-21.
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