Indiana football game Saturday: Indiana vs Michigan odds and prediction for NCAA Week 10 game

The Indiana Hoosiers face another tall task in Week 10, taking on the No. 9 Michigan Wolverines as Indiana looks to grab its first Big Ten win of the season. 

The Indiana Hoosiers continue to struggle in Big Ten play following a gut-wrenching 35-38 loss to Maryland. The Hoosiers now face their toughest task yet in Week 10 when they visit the No. 9 Michigan Wolverines in prime time.

Indiana vs Michigan Odds Week 10

The Week 10 betting odds on WynnBET have the Hoosiers as massive 19-point underdogs with -110 odds to cover.

Indiana will have to overcome +700 moneyline odds to come away with their first conference victory on Saturday. Michigan is -1100 in this matchup.

The over/under in this game is set at 50.0 with -110 odds on both the over and under.

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Indiana vs Michigan Prediction Week 10

There’s no doubt that this Michigan squad is one of the best in the country, as evidenced by their No. 9 ranking in the national polls.

One thing moving in Indiana’s favor is Michigan’s crushing Week 9 loss to Michigan State. That usually works in one of two ways: the Wolverines come out flat after a disappointing loss or come out firing on all cylinders.

Week 10 will be Indiana’s sixth contest against a ranked opponents. They’ve lost the previous five by an average of 23.6 points and this game will follow a similar pattern.

Michigan 38, Indiana 17

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